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  1. Apr 23, 2024 · Most people with dengue have mild or no symptoms and will get better in 1–2 weeks. Rarely, dengue can be severe and lead to death. If symptoms occur, they usually begin 4–10 days after infection and last for 2–7 days. Symptoms may include: high fever (40°C/104°F) severe headache. pain behind the eyes.

  2. Dec 21, 2023 · The global incidence of dengue has markedly increased over the past two decades, posing a substantial public health challenge. From 2000 to 2019, the World Health Organization (WHO) documented a ten-fold surge in reported cases worldwide increasing from 500 000 to 5.2 million. The year 2019 marked an unprecedented peak, with reported instances ...

  3. The dengue virus is a tiny structure that can only replicate inside a host organism. The four closely related dengue viruses — DEN-1, DEN-2, DEN-3, and DEN-4 — are found in the same regions of ...

  4. Mosquito-borne flaviviruses, including dengue virus (DENV) and Zika virus (ZIKV), are a growing public health concern. Systems level analysis of how flaviviruses hijack cellular processes through virus-host protein-protein interactions (PPIs) provide information about their replication and pathogenic mechanisms.

  5. Apr 5, 2024 · Mechanisms of bleeding in dengue. Patients with dengue may present with a wide range of bleeding manifestations such as petechiae, gum bleeding, increased bleeding from sites of venipuncture to hematemesis, melena, hematuria, epistaxis, and per vaginal bleeding [97,123]. The mechanisms leading to bleeding include thrombocytopenia, dysfunctional ...

  6. Jan 9, 2014 · Dengue viruses (DENV), a group of four serologically distinct but related flaviviruses, are responsible for one of the most important emerging viral diseases. This mosquito-borne disease has a great impact in tropical and subtropical areas of the world in terms of illness, mortality and economic costs, mainly due to the lack of approved vaccine ...

  7. Jan 16, 2023 · A study estimated the value of R0 during the 2014 Guangdong Province dengue outbreak in China to be around 1.74, and after implementing impulsive vector control strategies, it reduced to 0.17 , while the R0 for the 2017 dengue outbreak in Pakistan was estimated to be approximately 2.65 and another study estimated the R0 to be 8.16 .

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