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May 1, 2024 · Direct infection and activation of platelets by dengue virus (DENV), by non-structural protein NS1 and high-density lipoprotein (HDL) complexes through TLR4, and by serotonin and platelet-activating factor (PAF) generated by mast cell degranulation, together lead to platelet activation, aggregation, and bleeding.
Jan 15, 2023 · FcR-dependent ADE is the most common mechanism for a wide range of virus infection such as HIV, influenza A, dengue and Ebola. Cells which have FcR such as monocytes, B cells, neutrophils and macrophages are easily attached by the virus-antibody complexes because the Fc region of the antibody will bind on the cell surface with FcR which leads ...
Nov 19, 2023 · Dengue is a mosquito-borne disease that is transmitted by the bites of Aedes mosquitoes, including Aedes albopictus and Aedes aegypti.Globally, this mosquito-borne disease is regarded as the most common human arboviral infection. 1 More than 2,000 dengue-associated deaths and over 3.7 million dengue cases have already been reported from 70 countries/territories worldwide as of August 23rd ...
Jun 6, 2022 · Rash. Intense pain behind your eyes. Nausea or vomiting. Muscle, bone and joint pain. Dengue fever symptoms start to appear four to 10 days after a mosquito bite and can last three to seven days. About 1 in 20 people sick with dengue will develop severe dengue after their initial symptoms begin to fade.
Interaction with specific receptor (s) at the cell surface is one of the first events in the pathogenesis of Dengue virus. However, relatively little is known about these receptors. Cellular receptors in human monocytes and mouse neural cells are main target for the viral infection. The envelope protein of the virus (E-protein) plays important ...
Jan 9, 2014 · Dengue viruses (DENV), a group of four serologically distinct but related flaviviruses, are responsible for one of the most important emerging viral diseases. This mosquito-borne disease has a great impact in tropical and subtropical areas of the world in terms of illness, mortality and economic costs, mainly due to the lack of approved vaccine ...
Dengue fever is a mosquito-borne tropical disease caused by dengue virus. It is frequently asymptomatic; if symptoms appear they typically begin 3 to 14 days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin itching and skin rash. Recovery generally takes two to seven days.
