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  1. HYDROXYCHLOROQUINE (hye drox ee KLOR oh kwin) treats autoimmune conditions, such as rheumatoid arthritis and lupus. It works by slowing down an overactive immune system. It may also be used to prevent and treat malaria. It works by killing the parasite that causes malaria. It belongs to a group of medications called DMARDs.

  2. Mar 1, 2024 · Hydroxychloroquine is not effective against all strains of malaria, or against malaria in areas where the infection has been resistant to a similar drug called chloroquine. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus .

  3. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams (or less) per kilogram of body weight. (Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds.) Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day.

  4. Hydroxychloroquine is commonly used alongside other disease-modifying drugs including methotrexate – especially for rheumatoid arthritis. However, some drugs can interact with hydroxychloroquine. Indigestion remedies (for example, antacids including some over-the-counter preparations) can stop hydroxychloroquine being absorbed.

  5. Mar 28, 2023 · Taking hydroxychloroquine to treat COVID-19 may increase the risk of heart rhythm problems, blood and lymph disorders, kidney injury, liver problems and failure. More information can be found here. Hydroxychloroquine is used to treat autoimmune diseases including arthritis. While considered generally safe, several adverse events are associated ...

  6. Aug 23, 2021 · Hydroxychloroquine in Post-Exposure Prophylaxis. One randomized, double-blind, placebo-controlled trial included 821 post-exposure prophylaxis subjects, of whom 107 developed COVID-19 over 14 days. The 49 of 414 (11.8%) assigned hydroxychloroquine and 58 of 407 (14.3%) given placebo resulted in a nonsignificant relative risk (RR) of 0.83 ( P ...

  7. Jun 1, 2018 · Hydroxychloroquine is an immunomodulatory drug that has been used for 60 years to treat malaria and autoimmune diseases such as systemic lupus erythematosus and inflammatory arthritis, and potential new uses and benefits continue to emerge. Toxicity concerns have been addressed with updated prescribing recommendations.

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