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  1. Oct 19, 2020 · IARC defines a Group 2B classification as “the agent is possibly carcinogenic to humans.”. This category is used by IARC when there is only limited scientific evidence in human studies that a compound increases cancer risk in humans and when there is sufficient evidence of an increased cancer risk in experimental animals.

  2. When, based on mechanistic considerations, the agent belongs to a class of agents of which one or more is probably carcinogenic to humans (Group 2A) or carcinogenic to humans (Group 1). These scenarios may also occur simultaneously within a Group 2A classification. Group 2B: The agent is possibly carcinogenic to humans.

  3. The IARC Monographs classification indicates the strength of the evidence that a substance or agent can cause cancer. The IARC Monographs programme seeks to identify cancer hazards, meaning the potential for the exposure to cause cancer. However, it does not indicate the level of cancer risk associated with exposure at different levels or in ...

  4. Jul 13, 2023 · IARC is a WHO agency. Based on available data, the committee categorizes substances as group 1 (“carcinogenic to humans”), group 2A (“probably carcinogenic to humans”), group 2B ...

  5. Jun 16, 2023 · This infographic presents the categories used by the IARC Monographs on the Identification of Carcinogenic Hazards to Humans to classify a substance according to the level of certainty that the substance can cause cancer. This classification does not indicate the level of risk associated with exposure. View.

  6. IARC also notes there is limited evidence in people that PFOA can cause testicular and kidney cancer. IARC has classified PFOS as “possibly carcinogenic to humans” (Group 2B), based strong evidence that it has some key properties of a carcinogen in people who are exposed to it, and on limited evidence that it can cause cancer in lab animals.

  7. Jun 29, 2023 · IARC have, however, now changed the name to “IARC Monographs on the Identification of Carcinogenic Hazards to Humans”, which at least describes what they actually do. And at least, this time, there will be a risk assessment published by JEFCA, at the same time as the IARC assessment.