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  1. Two of the symptoms listed above are often early signs of scleroderma. The fingers may become: Highly sensitive to the cold and change color with cold or emotional stress (the symptoms of Raynaud’s phenomenon) Stiff and puffy. These symptoms happen because the blood vessels narrow due to spasm. Excess collagen can also damage blood vessels.

  2. Scleroderma is an autoimmune disease that causes inflammation and fibrosis (thickening) in the skin and other areas of the body. When an immune response tricks tissues into thinking they are injured, it causes inflammation, and the body makes too much collagen, leading to scleroderma. Too much collagen in your skin and other tissues causes ...

  3. Scleroderma means “hard skin.”. But this disease can affect more than the skin. Joints, muscles, and even internal organs like the kidneys and lungs can harden and tighten. Many people who have scleroderma lead normal—or almost normal—lives. Where you have the hardening and tightening varies with the type of scleroderma you have.

  4. This trait is what gives scleroderma its name. Some people develop 1 or 2 patches of hard, thick skin. Others have widespread patches on their body. The hard, thick skin can feel anchored in place. If you have morphea (more-fee-uh), the most common type of scleroderma, the patches may not feel too hard. In time, the hardened skin may soften.

  5. Browse millions of high-quality stock photos, illustrations, and videos. Search from Scleroderma stock photos, pictures and royalty-free images from iStock. Find high-quality stock photos that you won't find anywhere else.

  6. About Scleroderma. Scleroderma is a systemic autoimmune disease where the immune system mistakenly attacks and damages the body. The cause of scleroderma is not fully understood, but a lot is known. The disease most often affects people ages 30 to 50 years but it can develop at any age. Women get scleroderma more often than men.

  7. Dec 21, 2023 · Overall symptoms of scleroderma include: calcium deposits in connective tissues. a narrowing of the blood vessels to the hands and feet, known as Raynaud’s disease. problems of the esophagus ...

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