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  1. Mar 3, 2017 · The success of the treatment in sepsis depends on early diagnosis, immediately starting the appropriate antibiotic treatment and supporting treatment, and elimination of or recovery from the underlying disease. Protection is the most important way of reducing morbidity and mortality rates. Most of the attacks are nosocomial .

  2. Feb 4, 2021 · In this review, we seek to address the major pathogenesis of current categories of infection, sepsis and septic shock in patients with burn injury. In addition, the recent diagnostic tools and potential biomarkers, including C-reactive protein (CRP), procalcitonin (PCT) and cytokines, are intensively discussed. Go to:

  3. Jul 6, 2023 · Septic shock is the final, most severe form of sepsis and also the most difficult to treat. Patients in septic shock are often called the “sickest patients in the hospital,” as doctors, nurses, and other healthcare professionals work to save them from long-lasting complications or death. People are more likely to develop sepsis in the ...

  4. May 29, 2023 · Systemic inflammatory response syndrome (SIRS) is an exaggerated defense response of the body to a noxious stressor (infection, trauma, surgery, acute inflammation, ischemia or reperfusion, or malignancy, to name a few) to localize and then eliminate the endogenous or exogenous source of the insult. It involves the release of acute-phase reactants, which are direct mediators of widespread ...

  5. Sepsis is a life-threatening infection of the bloodstream by toxin-producing bacteria, which can develop anywhere in the body. Sepsis can accompany meningitis, infections of the bone in hospitalized patients, intravenous lines, surgical wounds or breaks in the skin. In sepsis, blood pressure drops, resulting in shock.

  6. May 22, 2018 · The risk of fluid overload. Treating a patient with septic shock inevitably results in some degree of salt and water overload. First and foremost, this is the result of the initial fluid resuscitation with the aim of restoring intravascular volume, increasing cardiac output, augmenting oxygen delivery and improving tissue oxygenation.

  7. Shock is the body's response to systemic inflammation. It can happen for a variety of reasons, not all of them dealing with bacteria. The main mediators in shock are IL1, IL6, and TNF-a. These three cytokines are secreted in the immune system and cause the whole body to go into a state of "shock" as the video describes.

    • 8 min
    • Ian Mannarino