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  1. It should be noted the U.S. Food and Drug Administration (FDA) has issued a statement that it disagrees with IARC’s classification of aspartame as a possible carcinogen to humans.

  2. Feb 24, 2015 · The IARC Monographs on the Evaluation of Carcinogenic Risks to Humans of the International Agency for Research on Cancer (IARC) are a prominent example of such an expert review process. The goal of the Monograph Programme is to assess carcinogenic hazards from occupational, environmental, and lifestyle exposures and agents, thus providing an ...

  3. Jul 14, 2023 · IARC classified aspartame as possibly carcinogenic to humans (Group 2B) on the basis of limited evidence for cancer in humans (specifically, for hepatocellular carcinoma, which is a type of liver cancer). There was also limited evidence for cancer in experimental animals and limited evidence related to the possible mechanisms for causing cancer.

  4. Jul 14, 2023 · The IARC’s grading system assigns products to Group 1 (carcinogenic), Group 2A (probably carcinogenic), Group 2B (possibly carcinogenic) and Group 3 (not classifiable). When something gets listed in Group 2B, as possibly carcinogenic, that usually means human data is lacking or inadequate and the agency is making an extrapolation from animal ...

  5. Jul 20, 2023 · Grade 1 substances are factors known to cause cancer in humans, with sufficient evidence supporting their carcinogenicity. This category includes smoking, asbestos, and processed meats, all of ...

  6. The International Agency for Research on Cancer (IARC) Monographs (www.monographs.iarc.fr) identify environmental and occupational causes of human cancer. Sometimes called the WHO “Encyclopedia of Carcinogens,” the IARC Monographs are critical reviews and evaluations of the weight of the evidence that an agent can increase the risk of ...

  7. Jul 13, 2023 · What else does the I.A.R.C. consider a possible carcinogen? The International Agency for Research on Cancer labeled aspartame as “possibly carcinogenic to humans,” a category that includes ...