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  1. Sepsis-3 Consensus Definitions are frequently cited as one paradigm. For patients under 18, please use the Pediatric SIRS, Sepsis, and Septic Shock Criteria. When to Use. Pearls/Pitfalls. Why Use. SIRS Criteria (≥2 meets SIRS definition) Temp >38°C (100.4°F) or <36°C (96.8°F) No. Yes.

  2. Sep 15, 2023 · Sepsis and the inflammatory response that ensues can lead to multiple organ dysfunction syndrome and death. The epidemiology, definitions, risk factors, clinical presentation, diagnosis, and outcomes of sepsis are reviewed here. The pathophysiology and treatment of sepsis are discussed separately.

  3. May 21, 2023 · Bacterial sepsis is a life-threatening condition that arises when the body’s response to an infection injures its tissues and organs. Sepsis has recently been re-defined as life-threatening organ dysfunction caused by a dysregulated host response to infection.[1] Sepsis, as a medical condition, was first introduced by Hippocrates (460 through 470 BC) and is derived from the Greek word sipsi ...

  4. Key Findings From Evidence Synthesis Limitations of previous definitions included an excessive focus on inflammation, the misleading model that sepsis follows a continuum through severe sepsis to shock, and inadequate specificity and sensitivity of the systemic inflammatory response syndrome (SIRS) criteria. Multiple definitions and ...

  5. In general, the incidence of sepsis is three to four-times higher, reflecting the relative percentage of patients who develop organ dysfunction and thus meet more severe definitions (severe sepsis or septic shock) . In the past decade we have realized that there have been significant longitudinal changes in the incidence of sepsis, most ...

  6. Dec 7, 2018 · ANSWER: Sepsis is a serious complication of an infection. It often triggers various symptoms, including high fever, elevated heart rate and fast breathing. If sepsis goes unchecked, it can progress to septic shock — a severe condition that occurs when the body’s blood pressure falls and organs shut down. Sepsis most often affects the ...

  7. Nov 13, 2023 · Sepsis happens when an infection you already have triggers a chain reaction throughout your body. Bacterial infections are the most common cause, but other types of infections can also cause it. The infections are often in the lungs, stomach, kidneys, or bladder. It's possible for sepsis to begin with a small cut that gets infected or with an ...

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