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May 9, 2023 · Pediatric sepsis remains an important cause of morbidity and mortality in children. This review will summarize the main aspects of the definition, the current evidence base for interventions discuss some controversial themes and point towards possible areas of improvement.
Sepsis is the leading cause of pediatric death worldwide. In the United States alone, there are 72,000 children hospitalized for sepsis annually with a reported mortality rate of 25% and an economic cost estimated to be $4.8 billion.
Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. [4] [7] This initial stage of sepsis is followed by suppression of the immune system. [8] Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. [1]
Oct 9, 2018 · The inability to isolate a microbial pathogen does not exclude sepsis (2, 3). The 2016 consensus definition of sepsis in adults (Sepsis-3) states that sepsis is “a life-threatening condition caused by a dysregulated host response to infection and organ dysfunction” .
Jan 12, 2021 · Background: Sepsis is the leading cause of death in burns. Despite its importance, sepsis lacks a proper definition. An established definition will lead to early and accurate diagnosis, prompt treatment, and a reduced mortality rate. The aim of this work ...
Sep 26, 2018 · The text has been structured in the following headings: epidemiology of sepsis in the world, evidences in sepsis detection programs, microbiological diagnosis, new evidence in initial resuscitation, usefulness of biomarkers, sepsis in pediatric patients, stewardship programs, new horizons for research, economic evaluation and the importance of ...
Dec 15, 2023 · Sepsis in children may present initially with non-specific, non-localised symptoms (especially in younger age groups). Therefore it is important to have a low threshold for suspecting sepsis as the initial clinical presentation of sepsis.
