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Mar 13, 2024 · COVID-19 is a respiratory infection caused by the SARS-CoV-2 virus. Most people with COVID-19 experience fever, fatigue, and respiratory symptoms. However, a small percentage may develop a rash and other skin manifestations associated with COVID-19 (i.e., COVID toes, urticaria, vesicular eruptions, and vaso-occlusive skin lesions).
The term bullous drug eruptions refers to adverse drug reactions that result in fluid-filled blisters or bullae. Blistering can be due to various medications, prescribed or over-the-counter, natural or synthetic. Blistering may be localised and mild, or widespread and severe, even life-threatening.
Morbilliform drug eruption is a measles -like rash that develops as a reaction to taking a drug. Any drug can trigger it, but the most common causes are antibiotics. The rash generally goes away after you stop taking the drug, although it may last 1-2 weeks. The rash could be itchy and be accompanied by a low-grade fever.
The drug eruption is an itchy maculopapular or morbilliform rash. It affects extensor surfaces and pressure points, face, neck, trunk, palms, and soles. It can involve the mucous membranes. The rash usually resolves within a week of discontinuing the antibiotic. The drug allergy is usually transient.
Jan 17, 2019 · The onset of a morbilliform eruption (MDE; also known as exanthematous or maculopapular drug eruption) typically occurs within 7 to 10 days after the initiation of the culprit drug. Occasionally a ...
Fixed drug eruption is a delayed type IV hypersensitivity reaction. In the initial phase memory CD8+ T-cells at the dermo- epidermal junction release interferon-gamma when activated by the medication antigen causing epidermal basal layer damage. Recruited T-cells and neutrophils damage melanocytes and keratinocytes.
Urticaria is one of the most common drug-induced skin eruptions, second only to morbilliform eruption. In outpatient dermatology clinics, drug-induced urticaria is estimated to affect 9% of patients presenting with urticaria. There does not appear to be any relationship to sex or race.
