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  1. OVERVIEW. Antidotes are agents that counteract the effects of a toxic agent on the body. They do not primarily affect the systemic absorption or removal of toxic agents from the body (i.e. decontamination and enhanced elimination respectively) Antidotes have a surprisingly minor role in the management of most poisonings, their use is restricted ...

  2. Antidotes are agents that negate the effect of a poison or toxin. Antidotes mediate its effect either by preventing the absorption of the toxin, by binding and neutralizing the poison, antagonizing its end-organ effect, or by inhibition of conversion of the toxin to more toxic metabolites.

  3. antidote, Remedy to counteract the effects of a poison or toxin.

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