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May 23, 2022 · The Wegovy group lost an average of almost 16% of their body weight. The Saxenda group lost an average of about 6%. There was no significant difference in stomach-related side effects. Aside from resulting in greater weight loss, Wegovy is a once-weekly injection. Saxenda is injected once daily.
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A 68-week trial by Novo Nordisk, who manufacture Wegovy, showed that patients using Wegovy achieved a mean change in body weight of 14.9% (compared to 2.4% in the placebo group). Of those, almost 85% achieved weight loss of ≥5%, 66% achieved weight loss of ≥10%, and almost 50% achieved weight loss of ≥15%.
