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  1. Neonatal sepsis is variably defined. There is remarkable heterogeneity among studies regarding the case definition of neonatal sepsis . The presence of a positive blood culture historically constitutes the “gold standard” for the presence of neonatal sepsis . This conclusion requires at least 2 assumptions: 1) the infant would not have been ...

  2. Mar 19, 2020 · Overview of neonatal sepsis and definitions. Sepsis represents a major contributor to global mortality and has been declared as a priority by the WHO. 1 The highest sepsis incidence across all age ...

  3. Neonatal sepsis is the cause of substantial morbidity and mortality. Precise estimates of neonatal sepsis burden vary by setting. Differing estimates of disease burden have been reported from high-income countries compared with reports from low-income and middle-income countries. The clinical manifestations range from subclinical infection to severe manifestations of focal or systemic disease ...

  4. Neonatal sepsis can be early onset (≤ 3 days of birth) or late onset (after 3 days). Early-onset sepsis usually results from organisms acquired intrapartum, and symptoms appear within 6 hours of birth. Late-onset sepsis is usually acquired from the environment and is more likely in preterm infants, particularly those with prolonged ...

  5. Jun 12, 2020 · Neonatal sepsis defines the systemic condition that arises from the bacterial, viral or fungal origin, associated with hemodynamic changes and clinical findings and causing severe morbidity and mortality. Its incidence varies depending on the definition of the case and the population studied and is between 1 and 5 in 1000 live births.

  6. Nov 6, 2021 · Neonatal sepsis is a leading cause of infant mortality worldwide with non-specific and varied presentation. We aimed to catalogue the current definitions of neonatal sepsis in published randomised ...

  7. Neonatal sepsis. Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) (such as meningitis, pneumonia, pyelonephritis, or gastroenteritis) in the setting of fever. Older textbooks may refer to neonatal sepsis as "sepsis neonatorum".

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