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  1. 3 days ago · Dengue virus (DENV) is a member of the flavivirus genus and is the cause of significant healthcare problems and economic burden worldwide, partially due to the lack of effective therapeutics and the limited efficacy of licensed vaccines, Dengvaxia and QDENGA (Bhatt et al., 2013; Diamond and Pierson, 2015). While the majority of DENV infections ...

  2. 5 days ago · It is composed of four distinct serotypes (DENV1, DENV2, DENV3, and DENV4), each capable of inducing a range of illnesses from dengue fever (DF) to more severe forms such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) [ 1, 2 ].

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  4. 3 days ago · Dengue virus (DENV) is a member of the flavivirus genus and is the cause of significant healthcare . ... 2014), the mechanism by which the oligomeric sNS1 with its lipid load in the central .

  5. 5 days ago · Source organism: Dengue virus 4 Philippines/H241/1956 Primary publication: The step-by-step assembly mechanism of secreted flavivirus NS1 tetramer and hexamer captured at atomic resolution.

  6. 4 days ago · The proposed additions, published on the preprint server medRxiv, split the current genotypes of the mosquito-borne virus into "major" and "minor" lineages to provide more spatiotemporal details, offer ways to assign lineages to sequence data, and propose new lineages.

  7. 4 days ago · Updated data as of epidemiological week 52 for Dengue, 52 for chikungunya and 52 for Zika of 2021. DENGUE. 1,269,271 cases. 127.94 cases x 100,000 Pop. 3,272 severe dengue (0.3%) 437 deaths. 0.034% case fatality rate (CFR) Saint Bartolome is he country with the highest cumulative incidence. CHIKUNGUNYA.

  8. 5 days ago · The findings suggested that the dengue virus produced using the Celcradle™ system possesses equivalent or superior immunogenicity to that from petri dishes. In summary, our findings shed light on Celcradle™ bioreactor's potential for large-scale production of inactivated dengue virus vaccines.

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