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  1. Feb 22, 2023 · In about one-third of people with ALS, symptoms begin with speech or swallowing difficulties, called bulbar onset. Early signs typically include: Changes in motor control of arms and hands: One hand or arm becomes weak, followed by the other a few weeks or months later. It may become more difficult to button a shirt or unlock a door.

  2. Mar 21, 2023 · Both mean a progressive loss of motor neurons, which means that a person with ALS will start to lose control of movements in their limbs, mouth, or throat. Early symptoms of ALS include: Muscle ...

  3. Apr 10, 2024 · Overview. Amyotrophic lateral sclerosis (a-my-o-TROE-fik LAT-ur-ul skluh-ROE-sis), known as ALS, is a nervous system disease that affects nerve cells in the brain and spinal cord. ALS causes loss of muscle control. The disease gets worse over time. ALS is often called Lou Gehrig's disease after the baseball player who was diagnosed with it.

  4. A gradual onset of progressive muscle weakness – which is generally painless – is the most common initial symptom of ALS. Other early symptoms vary but can include tripping, dropping things, abnormal fatigue of the arms and/or legs, slurred speech, muscle cramps and twitches and uncontrollable periods of laughing or crying.

  5. Jun 27, 2024 · ALS early symptoms. The first symptoms of ALS you might notice are muscle weakness and stiffness. These symptoms can affect your: Arms and legs (limb onset). Speech and swallowing (bulbar onset). It may be more difficult for you to do routine things, like writing your name or buttoning your shirt. You might need more time to eat meals than usual.

  6. Oct 6, 2022 · Early signs and symptoms of ALS may include the following: Tripping and falling or having a hard time walking. Feeling clumsy. Weakness in your hands, legs, feet, or ankles. Muscle cramps and ...

  7. ALS is progressive, meaning the symptoms get worse over time. The U.S. Food and Drug Administration has approved several drugs for ALS that may prolong survival, reduce the rate of decline, or help manage symptoms. However, there is currently no known treatment that stops or reverses the progression of ALS. Early symptoms include:

  8. Feb 27, 2023 · ALS, or amyotrophic lateral sclerosis, is a progressive neurodegenerative disorder affecting the motor neurons in the central nervous system. The early symptoms of ALS include muscle twitching or ...

  9. alsnetwork.org › newly-diagnosed-guide › early-als-symptomsEarly ALS Symptoms | ALS Network

    ALS usually progresses throughout one limb before spreading to another. Early signs of limb onset may include: Muscle weakness without pain. Muscle stiffness. Difficulty walking, including tripping and catching your foot on the ground. Difficulty with tasks that involve fine motor skills, like buttoning a shirt.

  10. Request an Appointment. 410-955-5000 Maryland. 855-695-4872 Outside of Maryland. +1-410-502-7683 International. Find a Doctor. Amyotrophic lateral sclerosis is a fatal neurological disorder characterized by progressive degeneration of nerve cells in the spinal cord and brain. It is often referred to as Lou Gehrig's disease.

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