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related to: von willebrand disease symptomsVisit HCP site to view resources for adult patients with von Willebrand disease.
Visit BleedingDisorders.com to learn the signs & symptoms of von Willebrand disease. Read about how symptoms of von Willebrand disease can vary, depending on the subtype.
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3 days ago · About von Willebrand disease (VWD) VWD is the most common hereditary bleeding disorder, with approximately 1% of the population having von Willebrand factor (VWF) levels below normal. The symptoms of VWD include frequent nose bleeds, skin bruises and haematomas, prolonged bleeds from small wounds, bleeding in the mouth, and excessive menstrual ...
3 days ago · Corticosteroids are used in combination with TPE in the acute phase, whereas rituximab is recommended for more severe presentations and for the treatment of refractory/relapsing disease. Caplacizumab, an anti-von Willebrand factor (VWF) nanobody, inhibits interaction between VWF multimers and platelets; its most common side effect is bleeding ...
3 days ago · Specific to vascular aging, IL-1β induces procoagulant NF-κB signaling cascade in endothelial cells, causing the release of von Willebrand factor, synthesis of plasminogen, and expression of p-selectin, e-selectin, intracellular adhesion molecule-1, and vascular cell adhesion molecule. 161,162 These factors promote the adhesion and migration ...
2 days ago · Local engagement. Connect with your local or area hemophilia chapter. These groups organize events, workshops, and support groups; my Florida chapter, for example, recently held an educational tea for women with bleeding disorders. Participating in such activities might allow you to meet others face to face, share experiences, and build lasting ...
5 days ago · Before using Calquence, be sure to tell your doctor about any bleeding problems, such as hemophilia or von Willebrand’s disease, that you have. Calquence may increase your risk of...
5 days ago · Von Willebrand disease. It has two types: Type 1. It is most common and VWF function is altered. The role of VWF is platelet adhesion and it also binds to factor 8. The quality and quantity of the factor will be deficient. Type 2. Von Willebrand factor multimers are destroyed by ADAM TS13. VWF factor is dysfunctional. Only quality is deficient.
1 day ago · Conditions that affect blood clotting, such as hemophilia or von Willebrand disease, can cause spontaneous bruising. Similarly, certain autoimmune disorders, like lupus or vasculitis, can cause inflammation of the blood vessels and result in unexplained bruises.
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related to: von willebrand disease symptomsVisit HCP site to view resources for adult patients with von Willebrand disease.
Visit BleedingDisorders.com to learn the signs & symptoms of von Willebrand disease. Read about how symptoms of von Willebrand disease can vary, depending on the subtype.
