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  1. 1 day ago · Pregnancy itself is a hyper-coagulation state characterized by an increase in coagulants (factors VII, VIII, IX, X, XII, fibrinogen, and von Willebrand factor [vWF]), decreased anticoagulant factors (protein C and protein S), and diminished fibrinolytic activities because of hormonal modifications to prevent excessive maternal hemorrhage.

  2. 1 day ago · 4. Von Willebrand Disease: In von Willebrand disease, the proportions of a specific glycoprotein called the von Willebrand factor reflect remarkable cutback and diminution. The depletion is prompted by an aberration in its corresponding genetic counterpart that masters and pilots its generations and functions. 5. Hereditary Spherocytosis:

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  4. 1 day ago · Exclusion criteria included a history of gastrointestinal, hepatic, or renal disease; history of hemophilia, von Willebrand disease, or lupus anticoagulant; history of a clinically significant nontraumatic bleed; any clinically important illness, medical/surgical procedure, or trauma within 4 weeks of first administration of AZD3366 or placebo ...

  5. 2 days ago · Examples include haemophilia A and B, and Von Willebrand syndrome. Thrombophilia: This term encompasses various blood clotting disorders where blood clotting is amplified and thrombi (blood clots) form more frequently. Thrombophilia can be inherited, or triggered by age or lifestyle factors (like smoking or obesity).

  6. 4 days ago · AFSTYLA ®, Antihemophilic Factor (Recombinant), Single Chain, is indicated in adults and children with hemophilia A (congenital Factor VIII deficiency) for: On-demand treatment and control of bleeding episodes. Routine prophylaxis to reduce frequency of bleeding episodes. Perioperative management of bleeding.

  7. 3 days ago · Von Willebrand disease (VWD) is the most common congenital bleeding disorder in the world. Despite its prevalance, many people, including some health care providers, do not know that VWD even exists. Dr. Fernando Corrales-Medina joined a team of VWD experts to create an online assessment to spread awareness about VWD.

  8. 5 days ago · Educators: Medical fraud at crisis pregnancy centers should make us rethink policy. Abortion rights advocates rally along Michigan Avenue in protest of so-called crisis pregnancy centers on May 13 ...

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