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  1. 22 hours ago · Gene expression analysis by qPCR was done according to the following procedure: The gene expression was conducted using TB Green® Premix Ex Taq™ II (Tli RNase H Plus) (Takara, Japan) as follows: 20 µL total reaction volume was obtained by adding 2 µL (80 ng) of cDNA to 10 µL of TB green mix, 1 µL of forward primer and 1 µL of reverse ...

  2. 4 days ago · The enigma emerged in the 1950s, when biologists discovered that the double helix of DNA encodes genes. Each gene consists of a series of genetic letters, and our cells read those letters to make ...

  3. 3 days ago · DNA methyltransferase 3A (DNMT3A) mutations are among the most common in hematologic malignancies of varying lineages1-8 and in the pre-malignant disorder clonal hematopoiesis (CH).9-13 This suggests DNMT3A mutations arise in multipotent stem/progenitor cells, confer a competitive advantage, and prime cells for malignant transformation. Conditional deletion of Dnmt3a in the murine ...

  4. 4 days ago · Researchers said the mutations occurred in a small “non-coding” gene, meaning it doesn’t provide instructions for making proteins. Until now, all but nine of the nearly 1,500 genes known to ...

  5. 3 days ago · Persson is best remembered for his one-year stint in the WHL. During the 2021-22 season, he was a fixture on the Kamloops Blazers blue line, recording 29 points in 65 games.

  6. 1 day ago · Figure 1 Spread of nitrogen data from the combined shoot and root material of two replicates. Comparing: (A) the water treatment, control (magenta) or reduced (RWT; orange), effect on the nitrogen concentration, and (B) the total treatment effect on the total plant nitrogen, separated by genotype, with the combined treatment including; precrop soil treatments of Peat compost (green), soil ...

  7. 1 day ago · The therapeutic options for neurodegenerative diseases have historically been very limited, primarily providing symptom relief rather than disease modification. The anti-amyloid monoclonal antibody, aducanumab, made history in 2021 by receiving accelerated Food and Drug Administration (FDA) approval as a disease-modifying agent against Alzheimer’s disease. Lecanemab followed by receiving ...

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