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5 days ago · Alpha-blockers. Alpha-blockers relax the smooth muscle of the prostate gland and bladder neck to relieve bladder outlet obstruction and improve urinary flow. When administered at their recommended therapeutic dose, alpha-blockers have comparable efficacy with reductions of 30% to 45% in symptom scores and improvements of 15% to 30% in urinary ...
2 days ago · Tamsulosin and alfuzosin are common alpha blockers often used as the first line of defense against BPH symptoms. They can provide relief for many individuals. 5-Alpha Reductase Inhibitors: These medications target the hormones (dihydrotestosterone) that cause the prostate to grow. Finasteride and dutasteride are common examples of these ...
2 days ago · These are experienced by 50% of men aged 50 years, increasing to 80% by 80 years of age. 1 Medical management – namely alpha blockers and 5-alpha reductase inhibitors – remains the mainstay of initial treatment. Inevitably, however, as our population becomes increasingly older, these treatments will fail and patients will need surgical ...
2 days ago · What Are Alpha Blockers Used For? An alpha blocker is commonly prescribed for the following conditions: Hypertension; Benign prostatic hyperplasia also known as enlarged prostate; Raynaud’s disease; Scleroderma which is characterized by thickening and hardening of skin; Pheochromocytoma, a tumor of adrenal gland
2 days ago · Barbalias GA, Nikiforidis G, Liatsikos EN. Alpha-blockers for the treatment of chronic prostatitis in combination with antibiotics. J Urol. 1998 Mar;159(3):883-7. Ackerman AL, Parameshwar PS, Anger JT. Diagnosis and treatment of patients with prostatic abscess in the post-antibiotic era. Int J Urol. 2018 Feb;25(2):103-10. Image references ...
2 days ago · The study also substantiated that alpha-blockers can reduce BPH progression (defined in this trial as a 4-point increase in the AUA Symptom Score [AUASS]), the development of acute urinary retention (AUR), and the need for surgical intervention.
2 days ago · For acute urinary retention, initial management includes bladder catheterization for prompt and complete decompression. If treatment with alpha-blockers is started at the time of catheterization, men with acute urinary retention from BPH are more likely to be able to return to normal voiding.
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