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  1. 3 days ago · Dengue virus (DENV) is a member of the flavivirus genus and is the cause of significant healthcare problems and economic burden worldwide, partially due to the lack of effective therapeutics and the limited efficacy of licensed vaccines, Dengvaxia and QDENGA (Bhatt et al., 2013; Diamond and Pierson, 2015). While the majority of DENV infections ...

  2. 5 days ago · It is composed of four distinct serotypes (DENV1, DENV2, DENV3, and DENV4), each capable of inducing a range of illnesses from dengue fever (DF) to more severe forms such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) [ 1, 2 ].

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  4. 2 days ago · Through mosquito bites, the dengue virus can infect humans and cause mild or severe sickness or death in some cases 1. The areas with a high Aedes mosquito population are most likely to experience ...

  5. 3 days ago · Dengue virus (DENV) is a member of the flavivirus genus and is the cause of significant healthcare ... (Akey et al., 2014), the mechanism by which the oligomeric sNS1 with its lipid load in the ...

  6. 5 days ago · The findings suggested that the dengue virus produced using the Celcradle™ system possesses equivalent or superior immunogenicity to that from petri dishes. In summary, our findings shed light on Celcradle™ bioreactor's potential for large-scale production of inactivated dengue virus vaccines.

  7. 4 days ago · The proposed additions, published on the preprint server medRxiv, split the current genotypes of the mosquito-borne virus into "major" and "minor" lineages to provide more spatiotemporal details, offer ways to assign lineages to sequence data, and propose new lineages.

  8. 5 days ago · Dengue is known to be transmitted primarily by a mosquito vector Aedes Aegypti, and in some instances, by Aedes albopictus. The dengue viruses are of two (2) genotypes – Asian 2 and Cosmopolitan; and four (4) serotypes - DEN1, DEN2, DEN3 and DEN4 which are circulating in the Philippines.

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