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4 days ago · Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Studies have indicated that immune dysfunction plays a central role in the pathogenesis of sepsis. Dendritic cells (DCs) play a crucial role in the emergence of immune dysfunction in sepsis. The major manifestations of DCs in the septic state are abnormal functions and depletion in ...
4 days ago · Sepsis is a global challenge and a significant burden in Sub-Saharan Africa. Here, Chenoweth et al profile host gene expression signatures from a cohort in Ghana to define molecular phenotypes and ...
2 days ago · Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. [4] [7] This initial stage of sepsis is followed by suppression of the immune system. [8] Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. [1]
1 day ago · The risk factors for severe pneumonia in older adult patients were age, COPD, congestive heart failure, chronic kidney disease, sepsis, respiratory rate, temperature, white blood cell count, procalcitonin, lactate, pH, and extent of lung involvement.
2 days ago · Lab findings include a WBC count of 18,000 with 5% bands, a creatinine of 1.5 mg/dL, a platelet count of 130 x 103/mm3, 80 WBCs on urinalysis with positive nitrite and leukocyte esterase, and a serum lactate of 1.2 mmol/L. After receiving ibuprofen and a fluid bolus, the patient feels better and states, “I need to go get my dog!”
3 days ago · |. May 31, 2024. In the REVEAL study, occurrence of thrombotic events were significantly associated with sustained hematocrit levels above 45% and WBC count higher than 11 x 109/L. Controlling both hematocrit and white blood cell count (WBC) are important strategies in managing polycythemia vera (PV), according to a study published in Blood.
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3 days ago · Despite the fact that red blood cell (RBC) transfusion is commonly applied in surgical intensive care unit (ICU), the effect of RBC transfusion on long-term outcomes remains undetermined. We aimed to explore the association between RBC transfusion and the long-term prognosis of surgical sepsis survivors.
