Search results
3 days ago · We identified 1209 eligible sepsis huddles among 604 infants. There were 111 culture-confirmed LOI episodes (9% of all huddles). Twelve clinical signs of infection poorly distinguished infants with and without LOI, with sensitivity for each ranging from 2 to 36% and AUROC ranging 0.49-0.53.
1 day ago · To the Editor We read with great interest the article “International Consensus Criteria for Pediatric Sepsis and Septic Shock”1 and commend the authors for their dedication to standardizing and improving the care of children with sepsis. By using an empirical approach in a global cohort of...
People also ask
What are the paediatric guidelines for sepsis management in children?
What is the presentation of neonatal sepsis?
What are the 2020 updated pediatric sepsis guidelines?
2 days ago · Over the last decade, antimicrobial resistance (AMR) has worsened to the point that around 50%–70% of common pathogens exhibit a high degree of resistance to available first- and second-line antibiotics. More than 214,000 newborn babies die of drug-resistant neonatal sepsis every year, mostly in low- and middle-income countries (LMICs).
1 day ago · Biofilm-related infections pose significant challenges in neonatal and pediatric care, contributing to increased morbidity and mortality rates. These complex microbial communities, comprising bacteria and fungi, exhibit resilience against antibiotics and host immune responses. Bacterial species such as Enterococcus faecalis, Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus ...
4 days ago · Objective To assess the impact of publication of UK National Institute for Health and Care Excellence (NICE) guidelines on the prevention and treatment of early-onset infections (EOIs) in neonates (clinical guideline 149 (CG149), published in 2012, and its 2021 update (NG195) on antibiotic use in very preterm infants. Design Interrupted time series analysis using data from the National ...
4 days ago · Out of 167 neonates, 13.77% were culture-positive for neonatal sepsis. Out of 23 organisms, 82.6% were resistant, while, 17.4% were not. Staph aureus was the major causative organisms. Among the Gram Positive and Negative bacteria, the highest sensitivity was observed for imipenum.
3 days ago · A total of 206 different antemortem clinical diagnoses were recorded. The most common clinical diagnosis among the enrolled cases was early onset neonatal sepsis (30/206, 14.6%), followed by perinatal asphyxia (24/206, 11.7%) and preterm baby (23/206, 11.1%) (Table 2). Other common diagnoses included low birth weight (21/206,10.2%) and ...
