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1 day ago · Empiric use of ampicillin and cefotaxime, compared with ampicillin and gentamicin, for neonates at risk for sepsis is associated with an increased risk of neonatal death. Pediatrics . 2006;117(1):67-74.
3 days ago · The discovery of antimicrobial drugs has led to a significant increase in survival from infections; however, they are very often prescribed and administered, even when their use is not necessary and appropriate. Newborns are particularly exposed to infections due to the poor effectiveness and the immaturity of their immune systems. For this reason, in Neonatal Intensive Care Units (NICUs), the ...
1 day ago · We performed a retrospective observational cohort study of neonatal patients with LOS treated with intravenous vancomycin. Empirical local guidelines for LOS were vancomycin (intermittent infusion) and piperacillin-tazobactam.
2 days ago · Pediatric sepsis is a serious issue globally and is a significant cause of illness and death among infants and children. Refractory septic shock and multiple organ dysfunction syndrome are the ...
5 days ago · Clinicians variably obtain anaerobic blood cultures as part of sepsis evaluations in the neonatal intensive care unit (NICU). Our objective was to determine if anaerobic blood culture bottles yielded clinically relevant information by either recovering pathogens exclusively or more rapidly than the concurrently obtained aerobic culture bottle ...
2 days ago · The decreased rate of overall use of prophylactic antibiotics is attributed to increased awareness and adherence to guidelines [49, 50] In children, suspected central nervous system infection and sepsis are very common life-threatening infections that requires antibiotics prescriptions [32, 45, 47]. Lack of access to affordable and rapid ...
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2 days ago · Critical Appraisal of the Literature. To evaluate clinically relevant articles regarding the diagnosis and early management of sepsis, severe sepsis, and septic shock, a search of the National Library of Medicine PubMed database was performed using the following search terms: sepsis management, septic shock management, and clinical sepsis treatment guidelines, with a date range of 2000 to 2018.
