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  1. These pathways help us spot and react to what might hurt us. They turn signals from harm into messages our brain can understand. By doing this, they help us feel pain and know when we’re at risk.

  2. 2 days ago · However, injury does not always lead to pain, with even severe injuries generating no pain in over a third of hospital admissions. Most of us also expect pain to resolve after healing, but persistent pain follows over 20% of surgeries, and pain afflicts 15-25% of the population in the absence of identifiable injury or disease.

  3. 1 day ago · A Bayesian brain hypothesis of pain perception as it applies to the placebo effect may have been first discussed by El-Deredy, Jones, and colleagues 13, 73 and has become a dominant viewpoint, 74 extended to nocebo effects 75 and pain perception in general. 76 Those converging accounts agree that the brain must maintain models of predicted pain ...

  4. 4 days ago · Abstract. Aim. To assess the emergency department practice context and identify strategies to improve outcomes of patients with acute pain. Background. Effective treatment of acute pain in the emergency department depends upon clinicians adopting pain interventions into practice. However, it is well-recognized that acute pain is often undertreated.

  5. 3 days ago · The myelin sheath is the insulating coating that protects your nerves and helps them quickly and efficiently send signals throughout your body. When the myelin coating is damaged, it can cause various medical conditions that slow or stop the transmission of these signals.

  6. 3 days ago · Objective To review and discuss the literature relevant to the role of brainstem structure and function in headache. Background Primary headache disorders, such...

  7. 2 days ago · Ketamine, a World Health Organization Essential Medicine, is widely used at varying doses for sedation, pain control, general anesthesia, and as a therapy for treatment-resistant depression. While scientists know its target in brain cells and have observed how it affects brain-wide activity, they haven’t known entirely how the two are connected.

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