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  1. 3 days ago · Abstract. Automated iterative small-molecule synthesis has the potential to advance and democratize the discovery of new medicines, materials and many other classes of functional chemical matter ...

  2. 1 day ago · PDF | Citrulline (C 6 H 13 N 3 O 3) is an amino acid found in the body as a zwitterion. ... that acts as a metabolic intermediate in the urea cycle and arginine synthesis. It is present in some ...

  3. 1 day ago · This process involves the formation of a five-membered intermediate through intramolecular radical addition, thus enabling the synthesis of thermodynamically disfavoured 1,2-cis-disubstituted ...

  4. 3 days ago · Organophosphorylated coumarin derivatives were synthesized by a three-component reaction of 4-chloro-3-formylcoumarin, aromatic amines, and dialkyl phosphite in the presence of ZnCl2. This process includes the formation of C(sp3)–P and C(sp2)–N bonds in one pot. The modular scope of the reaction allowed rapid access to a variety of 6H-chromeno[4,3-b]quinolin-7-ylphosphonate derivatives in ...

  5. 4 days ago · Lab Manuals. Advanced Organic Chemistry - Part A: Structure and Mechanisms. Advanced Organic Chemistry - Part B: Reactions and Synthesis. Arrow-Pushing in Organic Chemistry: An Easy Approach to Understanding Reaction Mechanisms. The Art of Problem Solving in Organic Chemistry. Biotransformations in Organic Chemistry: A Textbook.

    • Teri Vogel
    • 2017
  6. 1 day ago · Thiourea and its derivatives have become a significant focal point within the organic synthesis field, garnering attention for their diverse biological applications, including antibacterial, antioxidant, anticancer, anti-inflammatory, anti-Alzheimer, antituberculosis and antimalarial properties. My objective is to present a comprehensive and easily understandable analysis of recent ...

  7. 4 days ago · Amphidinol 3 (AM3, 1) is a super-carbon-chain compound produced by the dinoflagellate Amphidinium klebsii (Fig. 3.1) [ 1 ]. AM3 is known to induce not only antifungal activity but also hemolysis by increasing membrane permeability. Determination of the stereochemistry was carried out in 1999 [ 2] by extensive NMR analysis including the JBCA ...

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