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1 day ago · Scleroderma is a rare autoimmune disease in which the body produces too much collagen. Here are its causes, symptoms, diagnosis, and management.
1 day ago · CONQUEST, a platform clinical trial launched by the Scleroderma Research Foundation (SRF), is now enrolling people with interstitial lung disease associated with systemic scleroderma (SSc-ILD) at centers in the U.S. The study is analyzing two investigational therapies using a master protocol to compare both treatments with a shared placebo group.
16 hours ago · The accurate differentiation between drug-induced scleroderma-like lesions and SSc holds considerable clinical significance. Typically, scleroderma-like lesions are characterized by several distinct features, which include a temporal association between the administration of taxane-based agents and the onset of cutaneous sclerotic lesions ...
2 days ago · Introduction The “scleroderma” type capillaroscopic pattern is a reference pattern in rheumatolo-gy that is a diagnostic sign for systemic sclerosis (SSc) in an appropriate clinical context ...
2 days ago · Gastroesophageal reflux disease (GERD) is a major clinical finding in scleroderma patients. The reflux of gastric content into the esophagus and the resultant mucosal injury is not only facilitated by a lower LES pressure, but also by the inability of the lower esophagus muscle peristalsis to effectively clear the esophageal content.
2 days ago · Scleroderma renal crisis (SRC) is a rare, life-threatening complication of systemic sclerosis (SSc) and can sometimes be the first manifestation of the disease.1 A 56-year-old female presented with acute encephalopathy requiring intubation and a systolic blood pressure of 230 mmHg; no information was available about her medical history.
5 days ago · Scleroderma is a rare group of autoimmune diseases that negatively impacts thousands of Americans’ skin through the development of rough or tight patches, which may constrict the ability to move. It can also have negative consequences on the digestive system, heart, and lung functioning capabilities.
