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5 days ago · Seasonal malaria chemoprevention (SMC) is the provision of monthly, preventative, anti-malaria medication to young children at times when they are most at risk of severe disease.
5 days ago · Independent evaluations of the pilot introductions of the RTS,S vaccine demonstrated high public health impact: a vaccine-attributable 13% drop in mortality among children age-eligible for vaccination; substantial reduction in hospitalizations for severe malaria; and, access to at least one malaria prevention intervention (malaria vaccine or ...
- What is the malaria situation and who is most at risk?Despite progress, efforts to control malaria face many challenges. There were an estimated 247 million malaria cases and 619 000 malaria deaths glo...
- What is the WHO recommendation for the malaria vaccines?WHO updated their recommendation for malaria vaccines in October 2023. The updated recommendation is applicable to both RTS,S and R21 vaccines: W...
- What are the WHO-recommended malaria vaccines and who can be vaccinated?As of 2 October 2023, both the RTS,S/AS01 and R21/Matrix-M vaccines are recommended by WHO to prevent malaria in children. Malaria vaccines should...
- What do we know about the currently available WHO-recommended malaria vaccines?Both the R21 and RTS,S vaccines are shown to be safe and effective in preventing malaria in children and, when implemented broadly, are expected to...
- What are the next steps for roll-out of the malaria vaccines and where will it be available?Nearly 2 million children in Ghana, Kenya and Malawi have already been vaccinated with the RTS,S malaria vaccine since 2019 through the WHO-coordin...
- What does the recently updated WHO recommendation for malaria vaccines mean for children at risk of malaria?The addition of the second malaria vaccine, R21, to complement the ongoing rollout of the first malaria vaccine, RTS,S, is expected to result in su...
- What about the Malaria Vaccine Implementation Programme, MVIP: will the malaria vaccine pilots continue?The Malaria Vaccine Implementation Programme, MVIP, was designed to evaluate the public health use of the RTS,S vaccine in Ghana, Kenya and Malawi....
2 days ago · Malaria has several serious complications, including the development of respiratory distress, which occurs in up to 25% of adults and 40% of children with severe P. falciparum malaria. Possible causes include respiratory compensation of metabolic acidosis , noncardiogenic pulmonary oedema , concomitant pneumonia , and severe anaemia .
2 days ago · This discovery, published in Nature Microbiology last week, helps in understanding of how malaria parasites respond to drug-induced stress and develop resistance. “Malaria’s growing drug resistance to artemisinin, the current last-line antimalarial drug, is a global crisis that demands new strategies and therapeutics.
Malaria treatment in sub-Saharan Africa is faced with challenges including unreliable supply of efficacious agents, substandard medicines coupled with high price of artemisinin-based combinations. This affects...
2 days ago · The worst outcome is death. Tinto says 4,000 people died of malaria last year in Burkina Faso alone. In 2021, across Africa, it's estimated that 619,000 died of the mosquito-borne disease, most of ...
2 days ago · The vaccine — called R21/Matrix-M — will be used as part of children’s routine immunization. It comes as welcome news in a country plagued by one of the highest incidences of malaria worldwide; more than 1.7 million cases were reported in 2022. “Previous concerns about supply meeting demand are firmly behind us,” said Leila Pakkala ...
