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  1. 2 days ago · Management of bacterial meningitis and neonatal sepsis were perhaps the two most important infectious disease conditions that pediatric residents had to be well versed in for the inpatient setting. Performing a clean LP was a badge of honor, and everyone heard the news about a “bloody tap.” That has all changed in the past three decades.

  2. 13 hours ago · Background With the rapid development of perinatal medicine and neonatal resuscitation technology, neonatal mortality gradually reduces, but sepsis is still a neonatal critical illness and an important cause of death. The onset of sepsis in premature infants is insidious, and the clinical symptoms lack of specificity. The available laboratory tests exhibit limited sensitivity and specificity ...

  3. 4 days ago · Abstract. Background: Early diagnosis of sepsis and its severity is essential for timely management to improve patient survival. Aim of the work: define prognostic indicators of mortality in children presenting with sepsis.

  4. 13 hours ago · Summary. As under-5 mortality declines globally, newborn or neonatal mortality is becoming increasingly important. Depending on measurement and empirical data sources, calculation of the magnitude and trend of all-cause and cause-specific neonatal mortality ranges from direct methods to model-based estimates.

  5. 13 hours ago · Sepsis, a life-threatening condition caused by the body’s dysregulated response to infection, presents a significant challenge in clinical management. Timely and accurate diagnosis is paramount for initiating appropriate interventions and improving patient outcomes. In recent years, there has been growing interest in identifying biomarkers that can aid in the early detection and ...

  6. 2 days ago · In 4755 neonates (4.6%, 95% CI 4.5–4.7), antibiotic therapy was started for suspected EOS, and in 2399 neonates (2.3%, 95% CI 2.2–2.4), antibiotic treatment was continued beyond 48 h. Incidence of culture-proven EOS was 1.1 cases per 1000 live births (0.11%, 95% CI 0.09–0.14).

  7. 13 hours ago · BMC Pediatrics is an open access journal publishing peer-reviewed research articles in all aspects of health care in neonates, children and adolescents, as ...

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