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  1. 3 days ago · Early signs of sepsis may include a change in mental status and very fast breathing. Common signs of sepsis include: Fever or low body temperature (hypothermia) Shortness of breath. Shivering or chills. Severe pain or discomfort. Confusion or delirium. Lightheadedness due to low blood pressure. Rapid heartbeat.

  2. 1 day ago · As we enter a phase of endemicity, COVID-19 remains a substantial public health burden [1,2]. Since 2022, multiple lineages within the SARS-CoV-2 Omicron variant family have continued to drive COVID-19 infections globally, with new Omicron XBB subtypes likely to emerge through ongoing viral evolution [3]. In Singapore, steadily rising rates of COVID-19 infections, hospitalizations and ...

  3. 4 days ago · The kidney injury molecule (KIM)-1 is shed from proximal tubular cells in acute kidney injury (AKI), relaying tubular epithelial proliferation. Additionally, KIM-1 portends complex immunoregulation and is elevated after exposure to lipopolysaccharides. It thus may represent a biomarker in critical illness, sepsis, and sepsis-associated AKI (SA-AKI). To characterise and compare KIM-1 in these ...

  4. 1 day ago · Timely decisions for thrombolytic therapies can be improved by getting neurology and pediatric hematology or a stroke consult service involved early on. It is essential to highlight that the results of adult stroke trials testing antithrombotic treatments cannot be directly used for children due to different thrombus formation mechanisms.

  5. 2 days ago · As shown in Figure 1.1 below, the major causes of under-five mortality have been estimated as follows: pneumonia 28%, neonatal problems 25%, malaria 20%, diarrhoea 20%, measles 4%, AIDS 1% and other causes 2%. As you can also see in Figure 1.1, malnutrition is associated with nearly 60% of mortality in under-five children.

  6. 3 days ago · Waldenstrom’s macroglobulinaemia (WM) is a rare type of non-hodgkin lymphoma, characterised by the presence of a monoclonal IgM protein [1,2] . Approximately 350 people are diagnosed with WM in the UK each year [3] . It is more common in men than it is in women, and it is much more common among people of white ethnicity than people of black ...

  7. 3 days ago · COVID-19 and risks to the supply and quality of tests, drugs, and vaccines; Data for tracking SDGs: challenges in capturing neonatal data from hospitals in Kenya; Sources of multi-drug resistance in patients with previous isoniazid resistant tuberculosis identified using whole genome sequencing