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  1. Vertex is a biotechnology company that develops medicines for serious diseases, such as cystic fibrosis, sickle cell disease, and kidney disease. Learn about its latest news, clinical trials, acquisitions, and corporate responsibility report.

  2. Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry.

  3. Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko,...

  4. Dec 8, 2023 · CASGEVY is a CRISPR/Cas9 genome-edited cell therapy for sickle cell disease (SCD) that offers the potential of a functional cure by reducing vaso-occlusive crises. Vertex leads global development and commercialization of CASGEVY, with support from CRISPR Therapeutics.

  5. Jan 30, 2024 · Vertex announces positive results from Phase 3 program for VX-548, a selective NaV1.8 inhibitor, in the treatment of moderate-to-severe acute pain. VX-548 showed statistically significant improvement in pain compared to placebo and was safe and well tolerated in surgical and non-surgical pain conditions.

  6. Dec 8, 2023 · CASGEVY is a CRISPR/Cas9 genome-edited cell therapy for sickle cell disease (SCD) patients 12 years and older with recurrent vaso-occlusive crises. It is the first CRISPR-based gene-editing therapy approved in the U.S. and offers the potential of a functional cure by increasing fetal hemoglobin production.

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