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Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders. T Wang, K Hoekzema, D Vecchio, H Wu, A Sulovari, BP Coe, ... Nature communications 11 (1), 4932. , 2020....
Tianyun Wang. expand_more. Works (11) sort Sort. PSMC3 proteasome subunit variants are associated with neurodevelopmental delay and type I interferon production. Science Translational Medicine. 2023-05-31 | Journal article. DOI: 10.1126/scitranslmed.abo3189.
Nov 15, 2022 · Most genetic studies consider autism spectrum disorder (ASD) and developmental disorder (DD) separately despite overwhelming comorbidity and shared genetic etiology. Here, we analyzed de novo variants (DNVs) from 15,560 ASD (6,557 from SPARK) and 31,052 DD trios independently and also combined as br ….
Wang TIANYUN | Cited by 2,215 | of State Key Laboratory of Medical Genetics of China, Changsha | Read 77 publications | Contact Wang TIANYUN
Oct 1, 2020 · In addition to doubling the number of patients for many NDD risk genes, we present phenotype-genotype correlations for seven risk genes (CTCF, HNRNPU, KCNQ3, ZBTB18, TCF12, SPEN, and LEO1) based on this large-scale targeted sequencing effort.
- Tianyun Wang, Kendra Hoekzema, Davide Vecchio, Huidan Wu, Arvis Sulovari, Bradley P. Coe, Madelyn A....
- 2020
Abstract. Most large-scale genetic studies of autism have focused on the discovery of genes by proving an enrichment of de novo mutations in autism probands or characterizing polygenic risk based on the association of common variants.
Tianyun Wang, Ph.D. in Genetics, is an assistant professor in the Department of Medical Genetics at School of Basic Medical Sciences, and in the Neuroscience Research Institute at Peking University.
