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I am a physician scientist, researcher, educator, and advocate for children. My research is focused on understanding the fundamental biology of Ewing sarcoma, an aggressive bone and soft tissue tumor that impacts all ages with peak incidence in adolescents and young adults.
- Tumor Heterogeneity
- Epigenetics
- Metabolic Reprogramming
Sarcomas are complex tissues that are comprised of both cancer cells and normal cells, as well as extracellular matrix. Crosstalk and collaboration among all components of the tumor is necessary for local tumor growth as well as metastasis to distant sites. Importantly, our research has shown that Ewing sarcoma tumor cells are very dynamic and they...
Ewing sarcomas are characterized by the presence of gene fusions, most commonly EWS-FLI1, often without evidence of any other gene mutations. As such, changes in cell phenotype that promote metastatic progression are largely driven by non-genetic mechanisms. We are studying how disruption of normal epigenetic regulation of developmental programs le...
The process of rapid proliferation and tumor expansion exposes tumor cells to multiple sources of internal and external stress. Tumor cells have adapted ways to maintain cellular homeostasis that allow them to survive and thrive under conditions that would destroy less resilient cells. Among the most important of these adaptation mechanisms is meta...
Sep 18, 2020 · A native of Vancouver, B.C., Dr. Elizabeth Lawlor is thrilled to be back in the Pacific Northwest. And she’s equally excited about joining the research community in Seattle, as Lawlor and her...
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Elizabeth Lawlor, MD, PhD. Dr. Elizabeth Lawlor is associate director of the Ben Towne Center for Childhood Cancer Research. Her research focuses on Ewing sarcoma, an aggressive bone and soft tissue tumor that peaks in adolescence and for which new cures are needed. Read about the Lawlor Lab.
Lawlor, Elizabeth, MD, PhD | M3D PhD Program. Professor, Pediatrics: Hematology-Oncology. Program: M3D PhD Program. M3D Research Mentor. Research & Clinical Summary. I am a physician scientist, researcher, educator, and advocate for children.
Elizabeth R. Lawlor, M.D., Ph.D. Professor of Pediatrics, University of Washington; Associate Director, Ben Towne Center for Childhood Cancer Research, Seattle Children’s Research Institute; Aldarra Foundation Endowed Chair in Pediatric Solid Tumor Research, UW School of Medicine.
1100 Olive Way, Suite 100, Seattle, WA 98101. 206.884.0198 (phone) mail Email. Profile. Lab. Elizabeth R. Lawlor, MD, PhD. Professor Associate Director at Ben Towne Center for Childhood Cancer Research. Division (s) Hematology Oncology and Bone Marrow Transplant. Associated with Fellowship (s) Hematology-Oncology Fellowship.
