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Daniel Dominguez. Writer: SpongeBob SquarePants. Daniel Dominguez has written for television in the live-action, animated, adult and kid space since 2011. In addition to the writing credits listed here, Daniel has sold TV shows and features to Universal Cable Productions, Disney, Nickelodeon, and Dreamworks TV.
- Writer, Producer, Actor
- Daniel Dominguez
- Altered Rna-Protein Interactions in Cancer
- RNA Binding by Noncanonical Domains
- Cell Signaling and RNA Processing
RNA processing is massively altered in cancer. These observations can be explained by 1) mutations in RNA binding proteins that alter how they bind their target transcripts, 2) mutations in RNA sequences that are normally bound by specific RNA binding proteins. We use computational approaches and biochemical assays to characterize mechanisms underl...
Recent evidence indicates that non-canonical domains or even disordered regions also bind RNA. We employ large-scale biochemical approaches to study these interactions in vitro and and in vivo. Given the prevalence of low-complexity domains in the proteome and their association with disease, understanding how these domains interact with RNA will sh...
Cell signaling pathways are known to modulate gene expression. However, crosstalk/cross-regulation between RNA processing and cell signaling is not well understood. We use systematic screening approaches to dissect the impact of cell signaling pathways on RNA binding protein activity. This project involves the study of post-translational modificati...
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Writer: SpongeBob SquarePants. Daniel Dominguez has written for television in the live-action, animated, adult and kid space since 2011. In addition to the writing credits listed here, Daniel has sold TV shows and features to Universal Cable Productions, Disney, Nickelodeon, and Dreamworks TV.
Daniel Dominguez, PhD Assistant Professor. PostDoc - MIT Cambridge, MA PhD - UNC at Chapel Hill
We use experimental and computational approaches to study how RNA processing controls gene expression. We have open positions for graduate students, postdocs, research technicians, and undergraduate students. please inquire at didoming@email.unc.edu.