Search results
1976 PhD, University College of London. An internationally recognized cancer expert, Dr. Lane is most notable for his contributions to the discovery of the p53 tumor suppressor protein, named by him as "the guardian of the genome" and implicated in over 50 percent of all human cancers.
Sir David Philip Lane FRCP FRCSE FMedSci FRS FRSE (born 1 July 1952) is a British immunologist, molecular biologist and cancer researcher. He is currently working in the Department of Microbiology, Tumor and Cell Biology at the Karolinska Institute and is Chairman of Chugai Pharmabody .
KH Vousden, DP Lane. Nature reviews Molecular cell biology 8 (4), 275-283. , 2007. 2743. 2007. Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some, neoplasms. PA Hall, DA Levison, AL Woods, CCW Yu, DB Kellock, JA Watkins, ...
This page is about the research in David Lane group. Professor Sir David Lane. Photo: Ulf Sirborn. The protein p53, widely known as the guardian of the genome, was discovered by Prof. Sir David Lane in 1979 and has over the years been recognized as a tumor suppressor gene mutated in more than half of all malignant tumors occurring in adults.
David Lane is an immunologist and molecular cell biologist recognized for his work on tumor suppressor proteins and the use of immunochemical methods to study protein function and conformation. He is known particularly for his work on the p53 protein and its interactions with the Mdm2 and SV40 Large T protein.
Co-Founder. Professor Sir David Lane is a co-founder of FogPharma and one of the scientists credited with the landmark discovery of cancer gene p53 in 1979. p53, called the “guardian of the genome” is the most frequently mutated gene in human cancer as more than half of human tumors contain mutations in the gene.
Jul 22, 2013 · Professor Sir David Lane, an internationally recognized and respected cancer researcher widely known for his discovery of the p53 tumor suppressor protein, is the Scientific Director of the...
