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  1. May 14, 2024 · Dr. Westlake is a senior investigator at the NCI/CCR who studies membrane trafficking and signaling in ciliogenesis and ciliary diseases. He uses cell and zebrafish models, advanced microscopy and genetics techniques, and has published several papers on these topics.

  2. Dr. Westlake is a senior investigator at the Center for Cancer Research, NIH, who studies membrane trafficking and ciliogenesis. He uses advanced imaging and biochemical techniques to investigate the role of Rab GTPases and other regulators in ciliary signaling and disease.

  3. Christopher WESTLAKE | Cited by 4,392 | of National Institutes of Health, MD (NIH) | Read 65 publications | Contact Christopher WESTLAKE.

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  5. Jan 15, 2023 · Electronic address: chris.westlake@nih.gov. PMID: 35351373. PMCID: PMC9510604. DOI: 10.1016/j.semcdb.2022.03.021. Abstract. Ciliogenesis is a complex multistep process used to describe assembly of cilia and flagella. These organelles play essential roles in motility and signaling on the surface of cells.

  6. Selective Bibliography of Dr. Christopher J. Westlake Laboratory of Cell and Developmental Signaling, NCI Wednesday, September 21, 2022. 1. Zhao H, Sun J, Insinna C, Lu Q, Wang Z, Nagashima K, Stauffer J, Andresson T, Specht S, Perera S, Daar IO, Westlake CJ

  7. Jul 22, 2019 · Here, we demonstrate that through the LPA receptor 1 (LPAR1), serum lysophosphatidic acid (LPA) inhibits Rab11a-Rabin8 interaction and ciliogenesis. LPA/LPAR1 regulates ciliogenesis initiation via downstream PI3K/Akt activation, independent of effects on cell cycle.

  8. Quanlong Lü, Chuanmao Zhang, Christopher J. Westlake. Live-cell fluorescence imaging of ciliary dynamics. Biophysics Reports, 2021, 7(2): 101-110. doi: 10.52601/bpr.2021.210005

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