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  1. Dieter Hilpmann. Actor. IMDbPro Starmeter See rank. Play trailer 1:49. Hell (2011) More at IMDbPro. Contact info. Agent info. Dieter Hilpmann is known for Hell (2011) and Hexe Lilli: Der Drache und das magische Buch (2009). Add photos, demo reels. Add to list. Known for: Hell. 5.9. Gefangener. 2011. Hexe Lilli: Der Drache und das magische Buch.

    • Actor
    • 2 min
  2. Feb 12, 2019 · The binding sites, mode of action, and selectivity were elucidated using crystal structures of KRAS G12C -SOS1, SOS1, and SOS2. By preventing formation of the KRAS-SOS1 complex, these inhibitors block reloading of KRAS with GTP, leading to antiproliferative activity.

    • R.C. Hillig, B. Sautier, J. Schroeder, D. Moosmayer, A. Hilpmann, C.M. Stegmann, N.D. Werbeck, H. Br...
    • 2019
  3. Jan 25, 2019 · Since the late 1980s, mutations in the RAS genes have been recognized as major oncogenes with a high occurrence rate in human cancers. Such mutations reduce the ability of the small GTPase RAS to hydrolyze GTP, keeping this molecular switch in a constitutively active GTP-bound form that drives, unchecked, oncogenic downstream signaling.

  4. Watchlist. The Counterfeiters (2007) Dieter Hilpmann: Geisel Stein. It looks like we don't have any photos or quotes yet. Be the first to contribute! Add a photo or add a quote . See also. Release Dates | Official Sites | Company Credits | Filming & Production | Technical Specs. The Counterfeiters. Recently Viewed. Get the IMDb App.

  5. Dieter Hilpmann - Actor, Cameraman & Film Producer. Dieter Hilpmann is a member of Vimeo, the home for high quality videos and the people who love them.

  6. Jul 24, 2018 · Nature Chemical Biology. 2020. TLDR. Cytochrome P450 oxidoreductase is identified as a contributor to ferroptotic cell death by promoting phospholipid peroxidation in various cellular lineages and is suggested as a potential druggable target for developing antiferroptosis therapeutics.

  7. Eaton, John K., Laura Furst, Richard Ruberto, Dieter Moosmayer, André Hilpmann, Matthew J. Ryan, Katja Zimmermann et al. "Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles." Nat Chem Biol 16, no. 5 (2020): 497-506. DOI: 10.1038/s41589-020-0501-5.

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