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What is periaqueductal gray (PAG)?
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Is the periaqueductal gray activated?
Why is periaqueductal gray important?
The periaqueductal gray (PAG, also known as the central gray) is a brain region that plays a critical role in autonomic function, motivated behavior and behavioural responses to threatening stimuli. [1] [2] PAG is also the primary control center for descending pain modulation.
Jul 24, 2023 · Introduction. The periaqueductal gray (PAG) is a key structure in the propagation and modulation of pain, sympathetic responses as well as the learning and action of defensive and aversive behaviors. Most notably, the PAG is largely responsible for descending modulation of pain perception, both in inhibition and facilitation, as pain does not ...
- Miriam Mokhtar, Paramvir Singh
- MCG, Augusta University Medical Center
- 2021
- 2023/07/24
This review and meta-analysis aims at summarizing and integrating the human neuroimaging studies that report periaqueductal gray (PAG) involvement; 250 original manuscripts on human neuroimaging of the PAG were identified.
- Clas Linnman, Eric A. Moulton, Gabi Barmettler, Lino Becerra, David Borsook
- 10.1016/j.neuroimage.2011.11.095
- 2012
- 2012/03
Learn about the periaqueductal gray (PAG), a cell-dense region in the midbrain that surrounds the aqueduct of Sylvius. Find out its cytoarchitectural, anatomical, and functional features, and how it relates to other brain structures.
Jul 24, 2023 · Excerpt. The periaqueductal gray (PAG) is a key structure in the propagation and modulation of pain, sympathetic responses as well as the learning and action of defensive and aversive behaviors. Most notably, the PAG is largely responsible for descending modulation of pain perception, both in inhibition and facilitation, as pain does not depend ...
- Miriam Mokhtar, Paramvir Singh
- 2021
Jul 24, 2023 · The periaqueductal gray (PAG) is a key structure in the propagation and modulation of pain, sympathetic responses as well as the learning and action of defensive and aversive behaviors. Most notably, the PAG is largely responsible for descending modulation of pain perception, both in inhibition and facilitation, as pain does not depend on ...
Jul 24, 2021 · The periaqueductal gray (PAG) is a complex mesencephalic structure involved in the integration and execution of active and passive self-protective behaviors against imminent threats, such as immobility or flight from a predator.
