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In toxicology, the median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 is a toxic unit that measures the lethal dose of a given substance. The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration.
Feb 11, 2018 · Learn what the LD50 is and how it is used to measure the toxicity of a substance. Find out the advantages and drawbacks of this method and see examples of its applications.
The median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 (lethal concentration and time) of a toxin, radiation, or pathogen is the dose required to kill half the members of a tested population after a specified test duration.
Mar 9, 2021 · The dose of radiation expected to cause death to 50 percent of an exposed population within 30 days (LD 50/30). Typically, the LD 50/30 is in the range from 400 to 450 rem (4 to 5 sieverts) received over a very short period.
LD 50 and LC 50 are measures of acute toxicity that indicate the amount or concentration of a chemical that kills or harms 50% of test animals. Learn how these tests are done, what they mean for human health and safety, and how to compare different chemicals.
Aug 11, 2022 · The LD 50 is the dose that kills half (50%) of the animals tested (LD = "lethal dose"). It is a standardized measure for expressing and comparing the toxicity of chemicals.
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Jan 1, 2024 · The amount of a chemical agent that is expected to kill 50% of the test organisms when given directly under the test’s stated conditions. For many years, the gold standard for determining acute toxicity between toxicants and species was the LD50 value, first created in 1927.
