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Robert Joseph Lefkowitz (born April 15, 1943) is an American physician (internist and cardiologist) and biochemist. He is best known for his discoveries that reveal the inner workings of an important family G protein-coupled receptors, for which he was awarded the 2012 Nobel Prize for Chemistry with Brian Kobilka.
The Nobel Prize in Chemistry 2012. Born: 15 April 1943, New York, NY, USA. Affiliation at the time of the award: Howard Hughes Medical Institute, USA; Duke University Medical Center, Durham, NC, USA. Prize motivation: “for studies of G-protein-coupled receptors”. Prize share: 1/2.
May 6, 2024 · Robert J. Lefkowitz (born April 15, 1943, Bronx, New York, U.S.) is an American physician and molecular biologist who demonstrated the existence of receptors—molecules that receive and transmit signals for cells.
- Kara Rogers
A Bit About Robert J. Lefkowitz. Dr. Lefkowitz is the Chancellor’s Distinguished Professor of Medicine and Professor of Biochemistry at Duke University. He has been an Investigator of the Howard Hughes Medical Institute since 1976.
Professor of Biochemistry. Associate of the Duke Initiative for Science & Society. Member of the Duke Cancer Institute. Cardiology. Cardiac Biochemistry Research.
Born in a small Russian village, he was known as a child prodigy at a young age and ultimately immigrated to the United States to become head of the Theological Seminary of Yeshiva University in New York City. One of his sons, Harry, was an ordained Rabbi and a prominent mathematician.
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3611. 2002. Transduction of receptor signals by ß-arrestins. RJ Lefkowitz, SK Shenoy. science 308 (5721), 512-517. , 2005. 2140. 2005. A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.
