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  1. Brothers & Sisters is an American family drama television series that centers on the Walker family and their lives in Los Angeles and Pasadena, California. The series aired for five seasons on ABC from September 24, 2006, to May 8, 2011. For the entirety of its run, it was broadcast on Sunday nights following Desperate Housewives.

  2. Brothers & Sisters: Created by Jon Robin Baitz. With Dave Annable, Calista Flockhart, Rachel Griffiths, Ron Rifkin. The story of the drama surrounding a family's adult siblings.

  3. Sun, Sep 24, 2006. Kitty Walker returns home to California after having been estranged from her mother for three years; she also has a job offer and a marriage proposal to consider.

  4. Find out how to watch Brothers & Sisters. Stream the latest seasons and episodes, watch trailers, and more for Brothers & Sisters at TV Guide.

  5. Watch Brothers & Sisters with a subscription on Hulu, or buy it on Fandango at Home, Prime Video, Apple TV. Mother Nora continues to be the glue that holds the dysfunctional Walker clan...

  6. Watch the official Brothers and Sisters online at ABC.com. Get exclusive videos, blogs, photos, cast bios, free episodes.

  7. Start your free trial to watch Brothers & Sisters and other popular TV shows and movies including new releases, classics, Hulu Originals, and more. It’s all on Hulu. Family is everything in ABC's Brothers and Sisters.

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