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Pandora's Clock (also known as Doomsday Virus) is a 1996 NBC miniseries based on a novel by John J. Nance about a deadly virus on a Boeing 747-200 from Frankfurt to John F. Kennedy International Airport. Directed by Eric Laneuville, the film stars Richard Dean Anderson, Stephen Root, Jane Leeves, Robert Loggia and Daphne Zuniga and the script closely follows the book. Wikipedia