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  2. Samantha Who? is a sitcom about a woman who develops amnesia after a hit and run accident. The show ran on ABC from 2007 to 2009 and starred Christina Applegate, Jennifer Esposito, and Melissa McCarthy.

    • Sitcom
  3. Samantha Who?: Created by Cecelia Ahern, Donald Todd. With Christina Applegate, Jennifer Esposito, Kevin Dunn, Melissa McCarthy. A woman suffers from amnesia and is forced to find out who she really is.

    • (11K)
    • 2007-10-15
    • Comedy, Mystery, Romance
    • 22
  4. Watch the official Samantha Who? online at ABC.com. Get exclusive videos, blogs, photos, cast bios, free episodes.

  5. www.youtube.com › channel › UC8FbxTbvAiKTeFG-1N0hC3ASamantha Who? - YouTube

    Ever wanted a do-over in life? Samantha Newly gets one in the new comedy, Samantha Who? When an accident leaves Sam (Christina Applegate) with amnesia, she forgets her past but finds herself.

  6. Samantha Newly, the young vice president of a real-estate firm, is forced to start life over after a horrific hit-and-run accident leaves her with amnesia.

    • (28)
    • Christina Applegate
    • TV-PG
    • 2
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  8. Samantha's boss, billionaire Winston Funk, arrives at his twice-a-year visit at Chapman & Funk... and proposes to Samantha! And Samantha has no recollection of her past, secret (especially from Andrea) intimate relationship with Funk.

  9. Samantha Newly has been a bad, bad girl. But thanks to an 8-day coma, she can't remember a thing. Not the parents she hasn't talked to in years. Not the boyfriend she's cheating on. And not the former friend she ditched in grade school.

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