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- Season 2 overviewSep 28, 1968-Apr 12, 196925 episodesSeason 2 episodes1. The Silent Cry Sep 28, 1968
- A criminal's latest plot has the police baffled, but a deaf girl knows his plan.
- 2. Comes Up Rose Oct 5, 1968
- A woman on the run is sought by her husband, a syndicate of sophisticated thieves and Mannix.
- 3. Pressure Point Oct 12, 1968
- Wounded man stumbles into Mannix's home, mumbles cryptic message then passes out.
- 4. To the Swiftest Death Oct 19, 1968
- Mannix looks into the death of a race-car driver. Guest: Jill Ireland.
- 5. End of the Rainbow Oct 26, 1968
- A slip of paper with Mannix's name on it is found on the body of a recently released convict.
- 6. A Copy of Murder Nov 2, 1968
- A missing manuscript holds a key clue to a man's unsolved death; guests Barbara Rush, Michael Evans.
- 7. Edge of the Knife Nov 9, 1968
- A frightened surgeon (Fritz Weaver) needs Mannix's help when his son is kidnapped.
- 8. Who Will Dig the Graves? Nov 16, 1968
- A philanthropist (Barry Atwater) asks Mannix to locate his estranged wife, though believed dead.
- 9. In Need of a Friend Nov 23, 1968
- Mannix seeks new evidence to exonerate a man whom he helped convict of embezzlement years earlier.
- 10. Night Out of Time Dec 7, 1968
- A man wakes up one morning to find himself bloodied and his girlfriend missing.
- 11. A View of Nowhere Dec 14, 1968
- Mannix sees a murder committed but can't find a corpse or a report of the crime.
- 12. Fear I to Fall Dec 21, 1968
- Mannix is subpoenaed to testify in a murder case against an ex-con he once sent to jail.
- 13. Death Run Jan 4, 1969
- A small-town sheriff and a murderer target Mannix when he helps an old friend.
- 14. A Pittance of Faith Jan 11, 1969
- A group of 21 people hires Mannix to prove a model's death wasn't suicide; guest Larry Linville.
- 15. Only Giants Can Play Jan 18, 1969
- Mannix links the death of a petty criminal to a gubernatorial campaign.
- 16. Shadow of a Man Jan 25, 1969
- A wealthy businessman who once threatened Mannix is murdered.
- 17. The Girl Who Came in With the Tide Feb 1, 1969
- Mannix launches an investigation after police rule a woman's death accidental.
- 18. Death in a Minor Key Feb 8, 1969
- Mannix sets out to search for Peggy's missing boyfriend (Yaphet Kotto).
- 19. End Game Feb 15, 1969
- A vengeful kidnapper uses an old Army buddy to lure Mannix into a booby-trapped building.
- 20. All Around the Money Tree Feb 22, 1969
- Thieves, a beautiful woman and a Scotland Yard detective search for stolen loot.
- 21. The Odds Against Donald Jordan Mar 1, 1969
- A contractor (James Olsen) is missing and Mannix ponders different explanations.
- 22. Last Rites for Miss Emma Mar 8, 1969
- Mannix suspects Peggy's boyfriend (Robert Hooks) in a morphine theft.
- 23. The Solid Gold Web Mar 22, 1969
- A newspaper publisher hires Mannix to probe his daughter's (Sally Kellerman) odd behavior.
- 24. Merry-Go-Round for Murder Apr 5, 1969
- Mannix heads for Las Vegas to investigate a corpse and $250,000 -- both missing.
- 25. To Catch a Rabbit Apr 12, 1969
- Mannix fears he accused the wrong man of the murder of a respected family's youngest son.