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- OverviewSep 21, 2009-May 24, 201024 episodesEpisodes24. All Fall Down May 24, 2010
- A serial killer leaves cryptic hints and dead bodies for the team.
- 23. Time Bomb May 17, 2010
- The team investigates its own department when Horatio's ex-girlfriend is killed in an explosion.
- 22. Mommie Deadest May 10, 2010
- When a suburban mother is murdered, the CSIs uncover her family's dark past.
- 21. Meltdown May 3, 2010
- A jewelry heist ends in murder; Delko returns to investigate when evidence is stolen from the lab.
- 20. Backfire Apr 19, 2010
- A murder victim's spirit won't leave Calleigh alone until she solves his case.
- 19. Spring Breakdown Apr 12, 2010
- The team splits up to investigate three different murders during spring break.
- 18. Dishonor Mar 22, 2010
- After returning from war, Horatio's son seeks his help to solve a murder.
- 17. Getting Axed Mar 8, 2010
- The team investigates the murder of an unpopular receptionist.
- 16. L.A. Mar 1, 2010
- Jesse faces accusations of evidence tampering, so Horatio and Eric go to Los Angeles to clear him.
- 15. Miami, We Have a Problem Feb 8, 2010
- The team investigates a case of a man who was murdered in outer space.
- 14. In the Wind Feb 1, 2010
- The CSIs have 24 hours to determine if a man on death row is really guilty; Eric Delko returns.
- 13. Die by the Sword Jan 18, 2010
- A bizarre case involving a man who was chopped in half baffles the CSIs.
- 12. Show Stopper Jan 11, 2010
- When a musician bursts into flames during a concert, the CSIs expose the dark side of stardom.
- 11. Delko for the Defense Dec 14, 2009
- Eric Delko returns as an expert witness for the defense, pitting himself against his old team.
- 10. Count Me Out Dec 7, 2009
- The investigation of a dead census worker sends the team into a high-speed chase and an explosion.
- 9. Kill Clause Nov 23, 2009
- Deadly jellyfish are used as a murder weapon; a mysterious woman from Jesse's past returns.
- 8. Point of Impact Nov 16, 2009
- When the CSIs investigate what caused a car accident, both drivers' darkest secrets are revealed.
- 7. Bone Voyage Nov 9, 2009
- A severed leg found in the Everglades is linked to a girl who went missing in Las Vegas.
- 6. Dude, Where's My Groom? Nov 2, 2009
- The CSIs re-create a night of bachelor party debauchery to solve a murder and find a missing groom.
- 5. Bad Seed Oct 19, 2009
- Alexx Woods and Delko try to help the team stop a deadly outbreak in Miami.
- 4. In Plane Sight Oct 12, 2009
- When Miami's most-hated man is murdered, the CSIs search for the killer.
- 3. Bolt Action Oct 5, 2009
- Team members investigate when a trio of volleyball players suddenly drops dead on the court.
- 2. Hostile Takeover Sep 28, 2009
- To save hostages, Horatio must submit to a gunman's bizarre request.
- 1. Out of Time Sep 21, 2009
- As Delko's life hangs in the balance, Horatio reminisces about the formation of the team.