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What are the prognosis factors for scleroderma?
What is the prognosis of scleroderma sclerosis (SSc)?
Is localized scleroderma associated with increased mortality?
May 22, 2020 · Introduction. One of the most common—and potentially most devastating—manifestations of systemic sclerosis (SSc) is interstitial lung disease (ILD), a group of chronic lung conditions characterized by fibrosis and/or inflammation of the lung parenchyma. ILD, also called pulmonary fibrosis, is now the leading cause of SSc-related death 1 and ...
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Contemporary studies of systemic sclerosis consistently...
- Clinical and Genetic Factors Predictive of Mortality in Early Systemic Sclerosis
Systemic sclerosis (SSc; scleroderma) is a chronic disease...
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Apr 5, 2024 · Systemic sclerosis, also known as scleroderma, is a rare connective tissue disorder with an unknown and complex pathogenesis. Scleroderma can be divided into 2 primary forms—localized scleroderma (including morphea, linear scleroderma, and scleroderma en coup de sabre) and systemic sclerosis. Systemic sclerosis can be further classified as limited systemic sclerosis (formerly known as CREST ...
- Rotimi Adigun, Amandeep Goyal, Anis Hariz
- 2022/05/08
Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune connective-tissue disease. Once considered an untreatable and unpredictable condition, research advancements have improved our understanding of its disease pathogenesis and clinical phenotypes and expanded our treatment armamentarium. Early and accurate diagnosis is essential, while ongoing efforts to risk stratify ...
Aug 28, 2023 · INTRODUCTION. Systemic sclerosis (SSc; scleroderma) encompasses a spectrum of related disorders, most of which share a characteristic clinical feature of skin thickening due to an excess of collagen fibers. The simplest division of the scleroderma-related disorders is into localized ( table 1) and systemic forms ( table 2) (see "Clinical ...
Some will lose hair, have dry skin and sweat less all due to changes in the skin. Diffuse scleroderma can cause changes to the gastrointestinal tract, heart, lung or kidneys. Increasingly, physicians use markers in the blood called autoantibodies to help determine the course of scleroderma and overall prognosis.
Apr 3, 2019 · Background Data on survival and prognosis factors in incident cohorts are scarce in systemic sclerosis (SStc). To describe survival, standardized mortality ratio (SMR), and prognosis factors in systemic sclerosis (SSc), we analyzed a multicenter French cohort of incident patients and performed a systematic review of the literature and meta-analysis. Methods A multicenter, French cohort study ...
Scleroderma is an autoimmune disease in which the body produces too much collagen, a fibrous protein that is a major component of the body’s connective tissues, including the skin, muscles, bones, tendons, and cartilage. It is also found in the gastrointestinal tract, blood vessels, and other organs. In scleroderma, researchers believe the ...
