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What is stiff person syndrome?
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Dec 8, 2022 · December 8, 2022. Stiff-person syndrome is an autoimmune disorder of the nervous system, often resulting in progressive, severe muscle stiffness and spasms of the lower extremities and back. It also can affect other body regions.
- Sharing Mayo Clinic: Diagnosed with stiff-person syndrome
Diagnosed with stiff-person syndrome — an extremely rare...
- Specialized testing helps reverse effects of stiff-person ...
Stiff-person syndrome affects about one in every million...
- Sharing Mayo Clinic: Diagnosed with stiff-person syndrome
Feb 22, 2022 · Available for both serum and cerebral spinal fluid, the assay detects GAD 65, anti-glycine receptor, DPPX and amphiphysin antibodies. Mayo Clinic Laboratories recommends serum evaluation for individuals suspected of having classic stiff-person syndrome.
While varied in presentation, the unifying clinical and electrophysiologic characteristic of stiff-person spectrum disorders — which include classical stiff-person syndrome, focal stiff-person forms (stiff-limb and stiff-trunk), and a severe encephalomyelitic form known as progressive encephalomyelitis with rigidity and myoclonus (PERM ...
May 22, 2023 · Stiff person spectrum disorder (SPSD) is heterogeneous, and accurate diagnosis can be challenging. Methods. Patients referred for diagnosis/suspicion of SPSD at the Mayo Autoimmune Neurology Clinic from July 01, 2016, to June 30, 2021, were retrospectively identified.
Feb 8, 2023 · Autoimmune movement disorder is an umbrella term that covers conditions such as ataxia, chorea, myoclonus, and dystonia. Symptoms include a sudden speeding up or slowing down of a person’s body movements, resulting in uncontrollable muscle jerks or problems with balance.