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   Should you use a blood test for von Willebrand disease?

   • Obtain VWF:Ag and VWF:GPIbM assays and consider administering a BAT to document severity of bleeding. The panel recommends against relying on a bleeding assessment tool (BAT) to decide whether to order specific blood testing in patients with intermediate or high probability of von Willebrand disease (Strong recommendation, moderate certainty).

   Diagnosis and Management of von Willebrand Disease

   www.hematology.org/-/media/hematology/files/clinicians/guidelines/ash-slide-set--vwd-diagnosis-and-management-38.pdf?la=en&hash=AA61BD8D56FB31285862265C031138CE

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   Is von Willebrand disease outgrowing the laboratory diagnosis of Type 1?

   • Outgrowing the laboratory diagnosis of type 1 von Willebrand disease: a two decade study 68. The effect of ABO blood group on the diagnosis of von Willebrand disease

   ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand

   ashpublications.org/bloodadvances/article/5/1/280/474888/ASH-ISTH-NHF-WFH-2021-guidelines-on-the-diagnosis

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   Is VWF/FVIII a prophylaxis for von Willebrand disease?

   • Highly purified VWF/FVIII concentrates in the treatment and prophylaxis of von Willebrand disease: the PRO. WILL study 44.

   ASH ISTH NHF WFH 2021 guidelines on the management of von Willebr…

   ashpublications.org/bloodadvances/article/5/1/301/474884/ASH-ISTH-NHF-WFH-2021-guidelines-on-the-management

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2. ashpublications.org › bloodadvances › articleASH ISTH NHF WFH 2021 guidelines on the management of von ...

   ashpublications.org › bloodadvances › article

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   Jan 12, 2021 · Major therapies include use of desmopressin to induce endothelial release of stored von Willebrand factor (VWF) and factor VIII (FVIII) and use of VWF concentrates, including both plasma-derived and recombinant products, as well as adjuvant therapies, such as antifibrinolytic tranexamic acid.

3. www.hematology.org › - › mediaDiagnosis and Management of von Willebrand Disease

   www.hematology.org › - › media

   Tell the patient she does not meet criteria for a diagnosis of VWD because her VWF levels are greater than 30 IU/mL. Diagnose the patient with type 1 VWD and arrange for desmopressin trial with VWF levels 1- and 4-hours post administration. Diagnose the patient with type 1 VWD and obtain a VWF propeptide level.

4. www.hematology.org › von-willebrand-diseaseASH ISTH NHF WFH Clinical Practice Guidelines on von ...

   www.hematology.org › von-willebrand-disease

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   ASH guidelines are reviewed annually by expert work groups convened by ASH. Resources derived from guidelines that require updating are removed from the ASH website. These one-page snapshots provide a high-level summary of the ASH ISTH NHF WFH VWD Guidelines. Diagnosis of von Willebrand disease.

5. www.nhlbi.nih.gov › files › docsThe Diagnosis, Evaluation, and Management of von Willebrand ...

   www.nhlbi.nih.gov › files › docs

   Copies of the full VWD Guidelines report, as well as this Pocket Guide and a patient education brochure (“In Brief: Your Guide to von Willebrand Disease”) are available on the NHLBI Web site and from the NHLBI Health Information Center.

   • File Size: 308KB

   • Page Count: 8

6. www.bleeding.org › sites › defaultASH ISTH NHF WFH Guideline Recommendations for Management of ...

   www.bleeding.org › sites › default

   Jan 11, 2021 · Evidence-based recommendations for treatment of VWD in the setting of major and minor surgery, testing during invasive procedures, use of desmopressin, and use of von Willebrand factor (VWF) concentrate prophylaxis. VWD is the most common inherited bleeding disorder.

7. pubmed.ncbi.nlm.nih.gov › 33570647ASH ISTH NHF WFH 2021 guidelines on the management of von ...

   pubmed.ncbi.nlm.nih.gov › 33570647

   Jan 12, 2021 · PMCID: PMC7805326. DOI: 10.1182/bloodadvances.2020003264. Abstract. Background: von Willebrand disease (VWD) is a common inherited bleeding disorder. Significant variability exists in management options offered to patients.