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  2. Jan 27, 2022 · Causes. Scleroderma results from an overproduction and accumulation of collagen in body tissues. Collagen is a fibrous type of protein that makes up your body's connective tissues, including your skin. Doctors don't know exactly what causes this process to begin, but the body's immune system appears to play a role.

  3. Scleroderma is an autoimmune disease that causes inflammation and fibrosis (thickening) in the skin and other areas of the body. When an immune response tricks tissues into thinking they are injured, it causes inflammation, and the body makes too much collagen, leading to scleroderma.

  4. Feb 27, 2024 · Scleroderma is a long-lasting autoimmune disease that affects your skin, connective tissue, & internal organs. Learn about types, causes, risk factors, symptoms, diagnosis & treatment.

  5. What causes scleroderma? Researchers are looking into what actually causes scleroderma. We do know that this group of rare diseases is: NOT contagious. NOT a type of cancer. NOT an infection. We also know that a person develops scleroderma when the body makes too much collagen. This excess collagen is what causes the skin to thicken and harden.

  6. Feb 8, 2023 · SS causes an immune response that destroys healthy tissue as an autoimmune disease because your bodys immune system mistakenly thinks your tissue is a foreign...

  7. What causes scleroderma? Doctors do not know the exact cause of scleroderma, but they think that several factors may play a part in causing the disease: Genetic makeup. Genes can increase the chance for certain people to develop scleroderma and play a role determining the type of scleroderma they have.

  8. Though doctors don’t yet know what causes scleroderma, it’s thought to be caused by a mixture of genetic and environmental factors. Studies have linked a number of genes to scleroderma that may make people more susceptible to the condition.

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