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Dec 22, 2022 · Live-attenuated vaccines. Live vaccines use a weakened (or attenuated) form of the germ that causes a disease. Because these vaccines are so similar to the natural infection that they help prevent, they create a strong and long-lasting immune response.
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Attenuated vaccines function by encouraging the body to create antibodies and memory immune cells in response to the specific pathogen which the vaccine protects against. Common examples of live attenuated vaccines are measles, mumps, rubella, yellow fever, and some influenza vaccines.
- Live-attenuated vaccines. Live-attenuated vaccines contain live pathogens from either a bacteria or a virus that have been "attenuated," or weakened. According to Dr. Scully, live-attenuated vaccines are produced by selecting strains of a bacteria or virus that still produce a robust enough immune response but that does not cause disease.
- Inactivated vaccines. Inactivated vaccines take a live pathogen and inactivate or kill it. When the vaccine is then introduced to a human through a shot, for example, the inactivated pathogen is strong enough to create an immune response, however, is incapable of causing disease.
- Subunit vaccines. Subunit vaccines are made from a piece of a pathogen, not the whole organism, so they do not contain any live pathogens. Some important subunit vaccines are polysaccharide vaccines, conjugate vaccines, and protein-based vaccines.
- Toxoid vaccines. Toxoid vaccines use inactivated toxins to target the toxic activity created by the bacteria, rather than targeting the bacteria itself.
Apr 16, 2021 · Examples of live-attenuated vaccines. The most common live-attenuated vaccines include: Live-attenuated Influenza (flu) vaccines (LAIV) Measles, Mumps & Rubella (MMR) Polio –...
Jan 12, 2021 · Live-attenuated vaccine. A live-attenuated vaccine uses a living but weakened version of the virus or one that’s very similar. The measles, mumps and rubella (MMR) vaccine and the chickenpox and shingles vaccine are examples of this type of vaccine. This approach uses similar technology to the inactivated vaccine and can be manufactured at scale.
Apr 18, 2022 · Live, attenuated vaccines currently recommended as part of the U.S. Childhood Immunization Schedule include those against measles, mumps, and rubella (via the combined MMR vaccine), varicella (chickenpox), and influenza (in the nasal spray version of the seasonal flu vaccine).
May 24, 2023 · By contrast, non-live vaccines typically require at least three doses to achieve protection that fades over time and must be restored with booster doses. Live-attenuated vaccines. Offer long-lasting, even lifetime protection. Could cause a life-threatening infection in someone with a weak or suppressed immune system.
