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  1. Nov 11, 2014 · The spirochaete bacterium Borrelia burgdorferi sensu lato is the causative agent of Lyme disease, the most common tick-borne infection in the northern hemisphere. There is a long-standing debate regarding the role of pleomorphic forms in Lyme disease pathogenesis, while very little is known about the characteristics of these morphological variants.

    • Leena Meriläinen, Anni Herranen, Armin Schwarzbach, Leona Gilbert
    • 10.1099/mic.0.000027
    • 2015
    • 2015/03
  2. Borrelia burgdorferi is a microaerophile, requiring small amounts of oxygen in order to undergo glycolysis and survive. Like all other Borrelia sps., this bacterium is also gram-negative and a spirochete. Borrelia colonies are often smaller, rounded, and white with an elevated center. [7] B. burgdorferi possesses flagella that allow it motility.

  3. Jul 17, 2023 · Borrelia burgdorferi is a pathogenic spirochete responsible for Lyme disease via a tick vector. This spirochete causes a characteristic annular rash, arthritis, carditis, and in late stages, encephalopathy. This activity reviews the cause of lyme disease, its presentation and diagnosis and highlights the role of the interprofessional team in ...

    • Randi Tatum, Anthony L. Pearson-Shaver
    • 2023/07/17
    • PBCGME, Nova Southeastern University
  4. When Borrelia burgdorferi is Gram-stained, the cells stain a weak Gram-negative by default, as safranin is the last dye used. Borrelia , like most spirochetes, does have an outer membrane that contains an LPS-like substance, an inner membrane, and a periplasmic space which contains a layer of peptidoglycan.

  5. Borrelia burgdorferi Infection 1 Barbara J.B. Johnson 4.1 Introduction Serology is the only standardized type of clinical diagnosis of Lyme borreliosis (Lyme disease) in the USA. It is also the only type of diagnostic testing approved by the US Food and Drug Administration (FDA). Of the 77 devices cleared by the FDA for in vitro Borrelia ...

    • 481KB
    • Barbara J. B. Johnson
    • 16
    • 2011
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  7. Feb 28, 2024 · The cells stain a weak Gram-negative as safranin is the last dye used, but Borrelia burgdorferi is not classified as either Gram-positive or Gram-negative. Borrelia can be stained with Giemsa stain or other blood stains and can be seen in the standard light microscope. It is better viewed under a dark ground microscope or by silver impregnation ...

  8. May 31, 2019 · Introduction . Borrelia burgdorferi is an intriguing and unique bacterium. It is most notorious for being the primary causative agent of Lyme disease in North America 1.With more than 42,000 probable and confirmed cases reported to the Centers for Disease Control and Prevention (CDC) in 2017 and other estimates in the range of 300,000 cases annually in the US, Lyme disease is the most common ...

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